Number | Mutation | 15β [%] | 11α [%] | 9α [%] | 6β [%] | Progesterone |
---|---|---|---|---|---|---|
1 | WT-CYP106A2 | 67.9 | 18.0 | 5.4 | 8.7 | n.d.* |
2 | A395T/G397K | 11.2 | 20.0 | 45.1 | 23.7 | n.d.* |
3 | A395H/G397Y | 22.9 | 15.2 | 38.6 | 23.3 | n.d.* |
4 | A395I | 28.7 | 50.9 | 10.2 | 10.2 | n.d.* |
5 | A395E/G397V | 9.4 | 15.9 | 48.6 | 26.1 | n.d.* |
6 | A395R/G397K | 9.1 | 12.9 | 44.8 | 33.2 | n.d.* |
7 | A395M/G397S | 13.1 | 65.6 | 14.4 | 6.9 | n.d.* |
8 | A395R/G397I | 13.2 | 12.7 | 47.0 | 27.2 | n.d.* |
9 | A395K | 16.5 | 37.2 | 42.4 | 4.0 | n.d.* |
10 | G397W | 27.3 | 36.4 | 27.3 | 9.1 | n.d.* |
11 | A395F | 32.5 | 38.3 | 11.5 | 17.7 | n.d.* |
12 | A243V | 78.0 | 8.2 | 3.6 | 10.2 | n.d.* |
13 | A395W/G397K | 10.5 | 19.2 | 55.9 | 14.3 | n.d.* |
14 | A395E/G397Stop | 13.4 | 15.5 | 45.4 | 25.8 | n.d.* |
15 | A395S/G397Y | 18.5 | 13.7 | 41.1 | 26.8 | n.d.* |
16 | A395R/G397R | 8.8 | 14.9 | 45.8 | 30.6 | n.d.* |
17 | D217V/A395E/G397V | 7.5 | 23.2 | 55.9 | 7.9 | 5.4 |
18 | F165L/A395E/G397V | 11.3 | 17.2 | 59.7 | 11.0 | 0.9 |
19 | A106T/A395R/G397K | 13.0 | 22.4 | 57.4 | 6.8 | 0.4 |
20 | A243V/A395R/G397R | 11.8 | 17.6 | 49.7 | 8.3 | 12.7 |
21 | A106T/A395R/G397R | 12.9 | 14.9 | 56.2 | 13.3 | 2.7 |
22 | F173A | 9.7 | 32.5 | 44.1 | 5.0 | 8.6 |
23 | A243S | 3.4 | 4.6 | 2.4 | 82.7 | 6.9 |
24 | T247A | 11.7 | 13.1 | 45.7 | 24.3 | 4.3 |
25 | A243S/T247A | 14.6 | 13.2 | 48.0 | 20.7 | 20.7 |
26 | F173A/A243S/T247A | 13.6 | 6.5 | 8.7 | 57.2 | 19.1 |