Fig. 1From: Overexpression of glutathione synthetase gene improving redox homeostasis and chicken infectious bursal disease virus propagation in chicken embryo fibroblast DF-1The relative intensity of metabolites in glutathione metabolism in DF-1 cells with IBDV incubation. A Topological analysis of the metabolic profiles in DF-1 cells induced by IBDV. B–F Show a significant increase in the intracellular intensities of GSH, GSSG, cysteinylglycine, cysteine-glutathione disulfide, and 5-oxoproline in DF-1 cells infected with IBDV (IBDV, open circle) for 12, 18 and 36 h compared with uninfected controls (no IBDV, solid square). Raw area counts from three independent experiments performed in triplicate (N = 3) were normalized to protein levels. Error bars show ± s.d. of the meanBack to article page