From: Study on synthesis of ursodeoxycholic acid by reduction of 7-ketolithocholic acid in double aprotic solvents and molecular simulations
Solvents
LiCl (%)
C (%)
Yu (%)
Yc (%)
HMPA
0.1 M
94.2
10.7
21.1
0.2 M
98.5
12.3
24.8
0.3 M
–
DMPU
39.3
8.2
9.7
50.2
11.8
12.4
62.4
11.3
19.6
DMI
34
22
43.6
28.4
30.2
18.2