Table 3 Influence of the ratio of DMI to HMPA on the stereoselective electroreduction of 7K-LCA
Solvents | Conversion of 7K-LCA (%) | Yield of UDCA (%) | Yield of CDCA (%) |
|---|---|---|---|
10%HMPA + 90%DMI | 73.1 ± 1.4 | 28.3 ± 1.6 | 13.5 ± 0.5 |
15%HMPA + 85%DMI | 82.2 ± 0.3 | 31.6 ± 0.5 | 16.4 ± 0.3 |
20%HMPA + 80%DMI | 86.7 ± 0.4 | 34.3 ± 0.2 | 20.7 ± 0.2 |
30%HMPA + 70%DMI | 93.8 ± 0.2 | 39.4 ± 0.4 | 22.4 ± 0.3 |
40%HMPA + 60%DMI | 93.9 ± 0.3 | 50.4 ± 0.5 | 23.1 ± 0.4 |
50%HMPA + 50%DMI | 94 ± 0.7 | 67.8 ± 0.3 | 25.3 ± 0.2 |
60%HMPA + 40%DMI | 92 ± 0.3 | 58.9 ± 0.4 | 27 ± 0.5 |
70%HMPA + 30%DMI | 95 ± 1.4 | 58.6 ± 0.8 | 28.4 ± 0.9 |
80%HMPA + 20%DMI | 96.7 ± 0.7 | 58.5 ± 0.7 | 30 ± 0.7 |
90%HMPA + 10%DMI | 97.7 ± 0.5 | 47 ± 0.6 | 35.6 ± 0.5 |