Fig. 5From: An evolved pyrrolysyl-tRNA synthetase with polysubstrate specificity expands the toolbox for engineering enzymes with incorporation of noncanonical amino acidsStructural features of the 23/24-IPE-binding sites and the key residues. A Superposition of the binding conformations of 23 and 24 with the IPE-tRNAPyl monomer. 3-(3-thienyl)-L-alanine (23) is represented as cyan sticks, and 3-(2-thienyl)-L-alanine (24) is represented as salmon sticks. B Interaction between 24 and the surrounding residues. C Interaction between 23 and the surrounding residuesBack to article page