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Fig. 2 | Bioresources and Bioprocessing

Fig. 2

From: Collagen type II solution extracted from supercritical carbon dioxide decellularized porcine cartilage: regenerative efficacy on post-traumatic osteoarthritis model

Fig. 2

Effects of the Col II solution on knee pain in MNX-induced osteoarthritis in rats. Rats were divided into eight groups (n = 6). N group, Normal control; OA group, MNX alone; CS1 group, MNX + type II collagen (1 mg/ml); CS5 group, MNX + type II collagen (5 mg/ml); CS10 group, MNX + type II collagen (10 mg/ml); CCS group, MNX + cartilage + type II collagen; and HA group, MNX + Synvice-One Hyaln G-F 20 (8 mg/ml). Data are expressed as mean ± SD (n = 6). *p < 0.05 compared with N group; #p < 0.05 compared with OA group; †p < 0.05 compared with HA group (n = 6)

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