Bioresources and Bioprocessing

Table 5 Reactant scope of V15CNF for Henry reaction

From: Rationally introducing non-canonical amino acids to enhance catalytic activity of LmrR for Henry reaction


Entry	R	Time^a /h	Yield^b /%
1	p-NO₂	8	99.2
2	m-NO₂	8	97.8
3	o-NO₂	8	98.4
4	p-Br	8	66.7
5	p-CH₃	8	57.4
6	H	8	55.6

^aReaction conditions: aldehyde (12 mmol/L), nitromethane (48 mmol/L), V15CNF (0.3 mg) and buffer (1 mL, pH 8.0) at 40 °C for 8 h
^bYield of product detected by HPLC

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