Bioresources and Bioprocessing is associated with the State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology​​​​​​​.
Structure-guided engineering of a flavin-containing monooxygenase for the efficient production of indirubin
Indirubin is a bisindole compound for the treatment of chronic myelocytic leukemia. Here, we presented a structure-guided method to improve the activity of a flavin-containing monooxygenase (bFMO) for the effi...