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Table 3 Batch fermentations of L-lysine-, L-ornithine-, and lycopene-producing strains in minimal medium with D-galacturonate or D-glucuronate

From: Engineering of Corynebacterium glutamicum for growth and production of L-ornithine, L-lysine, and lycopene from hexuronic acids

  

D-galacturonate

D-glucuronate

L-lysine by DM1933(pHexA)(pVWEx1 - exuT)

  
 

C Lys (mM)

6.5 ± 0.2

9.3 ± 1.1

 

μ (h−1)

0.01 ± 0.01

0.02 ± 0.01

 

Y p/s (gLys gsubstrate −1)

0.04 ± 0.01

0.07 ± 0.01

Lycopene by ΔcrtYEb (pHexA) (pVWEx1- exuT )

  
 

C Lyc (mg/g)

0.7 ± 0.1

0.8 ± 0.3

 

μ (h−1)

0.02 ± 0.01

0.04 ± 0.01

 

Y p/s (gLyc gsubstrate −1)

0.09 ± 0.01

0.08 ± 0.02

L-ornithine by ORN1(pHexA) (pVWEx1- exuT )

  

 With 0.75 mM L-arginine

C Orn (mM)

2.4 ± 0.2

<0.5

 

μ (h−1)

0.03 ± 0.01

0.03 ± 0.01

 

Y p/s (gOrn gsubstrate −1)

0.01 ± 0.01

<0.01

 With 0.125 mM L-arginine

C Orn (mM)

1.7 ± 0.1

0.6 ± 0.2

 

μ (h−1)

0.04 ± 0.01

0.03 ± 0.01

 

Y p/s (gOrn gsubstrate −1)

0.01 ± 0.01

<0.01

  1. CGXII minimal medium was used with 100 mM of the indicated carbon source.