Biocatalytic synthesis of ethyl (R)-2-hydroxy-4-phenylbutyrate with a newly isolated Rhodotorula mucilaginosa CCZU-G5 in an aqueous/organic biphasic system

Bioresources and Bioprocessing

Table 2 Comparison between R. mucilaginosa CCZU-G5 and other reported microorganisms

Strain	Reaction media	OPBE conc	Reaction time (h)	ee (%)	Yield (conversion) (%)	References
R. mucilaginosa CCZU-G5	Aqueous phase	20 mM	8	99.2 (R)	76.3	This study
	Aqueous/isooctane	100 mM^a	12	>99.0 (R)	98.3	This study
	Aqueous/isooctane	200 mM^a	12	>99.0 (R)	>80	This study
Saccharomyces cerevisiae	Water/benzene	400 mM	48	87.5 (R)	(41.9)	Shi et al., 2009 [28]
Candida krusei SW2026	Water/dibutyl phthalate	100 mM	16	97.4 (R)	82	Zhang et al., 2009 [8]
Candida krusei SW2026	Aqueous phase	10 mM	14	99.7 (R)	95.1	Zhang et al., 2009 [8]
Candida boidinii CIOC21	Aqueous phase	20 mM	12	99.0 (R)	92	Chen et al., 2009 [12]
Pichia angusta	Aqueous phase	0.14% in volume	24	81 (R)	(100)	Lacerda et al., 2006 [7]