Figure 1From: Bioreductive preparation of ACE inhibitors precursor (R)-2-hydroxy-4-phenylbutanoate esters: Recent advances and future perspectives Various approaches for the synthesis of selected ACE inhibitors building blocks. (1) Enantioselective resolution of rac-HPBE, (2) asymmetric ene reduction, (3) asymmetric reduction of ene and carbonyl groups, (4) asymmetric reduction of OPBE, (5) hydrogenolysis, and (6) enantioselective hydrolysis of rac-hydroxynitrile.Back to article page