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Table 1 Influence of DMSO on the stereoselective electroreduction of 7K-LCA

From: Preparation of ursodeoxycholic acid from 7-ketone lithocholic acid by stereoselective electroreduction

No. DMSO content (mM) Supporting electrolyte Conversion of 7K-LCAa (%) Yield of UDCAa (%)
1 KBr 48 18.8
2 107.5 KBr 88.5 72.8
3 317.6 KBr 92.5 16.6
4 521.5 KBr 51.7 20.1
  1. Cathode: lead; anode: titanium-ruthenium mesh; 7K-LCA concentration: 0.04 M; supporting electrolyte concentration: 0.08 M; current density: 2.1 mA cm−2; temperature: 65 °C
  2. aConversion based on the starting material and the purity of UDCA determined by HPLC analysis