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Table 3 Effect of asparagine to glutamine ratio on ATP production rate

From: Responses of CHO-DHFR cells to ratio of asparagine to glutamine in feed media: cell growth, antibody production, metabolic waste, glutamate, and energy metabolism

Culture

Lactate production rate (mmolC/109cells/day)

Oxygen consumption rate (mmolC/109cells/day)

ATP production rate (mmolC/109cells/day)

FB-L

0.322 ± 0.032***

4.805 ± 0.201*

28.508 ± 1.411*

FB-H

−0.403 ± 0.029

5.760 ± 0.156

34.963 ± 1.152

FB-N

−0.299 ± 0.014

3.612 ± 0.098

21.901 ± 0.997

  1. The p value was calculated between FB-L and FB-H
  2. 0.01 < * p < 0.05, 0.001 < ** p < 0.01, *** p < 0.001