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Table 1 Process variables used central composite design with actual factor levels corresponding to coded factor level

From: Improvement of chaetominine production by tryptophan feeding and medium optimization in submerged fermentation of Aspergillus fumigatus CY018

Independent variables (g/L) Symbols Code levels
−1 0 +1
Sucrose A 80 100 120
Ammonium acetate B 3 3.5 4
d-Tryptophan C 3.3 4.3 5.3