Fig. 5From: Penicillin acylase-catalyzed synthesis of N-bromoacetyl-7-aminocephalosporanic acid, the key intermediate for the production of cefathiamidineEffect of the substrate concentrations on the synthesis of N-bromoacetyl-7-ACA. Reaction conditions: 7-ACA of the designated concentration, substrate molar ratio (methyl bromoacetate/7-ACA) of 3, 3 U/mL PGA-750, 10 mL phosphate buffer (100 mmol/L, pH 7.5), 200 r/min, 20 °CBack to article page