Fig. 6From: Penicillin acylase-catalyzed synthesis of N-bromoacetyl-7-aminocephalosporanic acid, the key intermediate for the production of cefathiamidineEffect of enzyme dosage on the synthesis of N-bromoacetyl-7-ACA. Reaction conditions: 50 mmol/L 7-ACA, 150 mmol/L methyl bromoacetate, PGA-750 of the designated dosage, 10 mL phosphate buffer (100 mmol/L, pH 7.5), 200 r/min, 20 °CBack to article page