Fig. 3From: Comprehensive reconstruction and evaluation of Pichia pastoris genome-scale metabolic model that accounts for 1243 ORFsEffects of each parameter change on specific growth rate and specific oxygen uptake rate for sensitivity analysis with iRY1243. The simulations were performed by varying the lipid content (6.2–16.2%) (a1, a2), protein content (37–47%) (b1, b2), RNA content (6.6–16.6%) (c1, c2), DNA content (0.1–1%) (d1, d2), carbohydrate content (26.9–36.9%) (e1, e2), and the NGAN (1.26–3.78 mmol ATP/gDCW h) (f1, f2). Red represents the simulated results for the maximum values of the input parameters, and black represents the lower content in all casesBack to article page