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Table 1 Comparison of ILEAE with the reference and conventional methods

From: Ionic liquid-based enzyme-assisted extraction of chlorogenic acid from Flos Lonicera Japonicae

Method

Optimized extraction parameters

CGA yield (%)

WE

Liquid ratio 10 ml/g, extraction temperature 75 °C, extraction time 1 h

2.29 (Yu et al. 2010)

Liquid ratio 15 ml/g, extraction temperature 70 °C, extraction time 1 h

3.8 (Li et al. 2011)

REE

Ethanol concentration 80% (v/v),extraction temperature 70 °C, extraction time 80 min

3.63 (Li and Hou 2013)

Ethanol concentration 75% (v/v), flocculation time 24 min, reflux time 1.5 h

3.81 (Xiao and Li 2011)

UAE

Soaking time 12 h, ultrasonic time 45 min, ethanol concentration 60%

5.62 (Lu et al. 2015)

MAE

Microwave power 300 W, microwave time 3 min, extraction temperature 60 °C, ethanol concentration 70% (v/v), extraction time 20 min

5.16 (Cao et al. 2008)

EAE

Dosage of pectinase 0.5%, operating temperature 45 °C, extraction time 120 min

4.55

ILEAE

0.75 M [C6mim]Br, extraction time 40 min, extraction temperature 70 °C, pH 4.0, 1 mg/ml pectinase

6.06