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Table 1 Summary of known azoreductases from different bacteria

From: Azoreductase: a key player of xenobiotic metabolism

Sr. no Organism Aerobic/anaerobic Flavin/NAD(P)H dependence Thermal stability in  °C (time) Molecular mass (kDa) References
1 Pseudomonas KF46 Aerobic NAD(P)H 30 32 Zimmermann et al. (1982)
2 Escherichia coli Aerobic FMN/NADH NA 23 Nakanishi et al. (2001)
3 Bacillus sp. OY1-2 Aerobic NAD(P)H 70 20 Suzuki et al. (2001)
4 Xenophilus azovorans KF46F Aerobic NAD(P)H (flavin free) NA 30 Blumel et al. (2002)
5 Pigmentiphaga kullae K24 Aerobic NAD(P)H NA 20.6 Blumel and Stolz (2003)
6 Rhodobacter sphaeroides AS1.1737 Aerobic NADH/NADPH NA 18.7 Bin et al. (2004)
7 Enterococcus faecalis Aerobic FMN/NADH NA 23 Chen et al. (2004)
8 Pseudomonas aeruginosa Aerobic NADH 35 29 Nachiyar and Rajakumar (2005)
9 Staphylococcus aureus Aerobic FMN/NADPH 55 85 (tetramer) Chen et al. (2005)
10 Bacillus sp. Aerobic NADH 45 23 Ooi et al. (2007)
11 Pseudomonas aeruginosa PAO1 Aerobic NAD(P)H 50 (10 min) 23 Wang et al. (2007)
12 Pigmentiphaga kullae K24 Aerobic NADPH (flavin free) NA 22 Chen et al. (2010)
13 Geobacillus stearothermophilus Aerobic FMN/NADH 65 (1 h) 23 Matsumoto et al. (2010)
14 Bacillus badius Aerobic NADH 60 43 Misal et al. (2011)
15 Bacillus lentus BI377 Aerobic NAD(P)H 70 (3 days) 32 Oturkar et al. (2013)
16 Aquiflexum sp. Aerobic NADH/NADPH 80 80 Misal et al. (2013)
17 Pseudomonas putida MET94  Aerobic NAD(P)H NA 21 Gonçalves et al. (2013)
18 Brevibacillus laterosporus TISTR1911 Aerobic FMN/NADH NA 23 Lang et al. (2013)
19 Lysinibacillus sphaericus Aerobic NADH (flavin free) 70 (30 min) 29 Misal et al. (2014)
20 Shewanella xiamenensis BC0 Aerobic NAD(P)H 20 26 Zhang et al. (2016)
21 Halomonas elongata Aerobic NADH NA 22 Eslami et al. (2016)
22 Rhodococcus opacus 1CP Aerobic NAD(P)H 40 25 Qi et al. (2016, 2017b)
23 Clostridium perfringens Anaerobic FMN/NADH NA 90.4 (tetramer) Morrison et al. (2012)
24 Shewanella oneidensis MR-1 Anaerobic NADH 25 27 Yang et al. (2013)
  1. NA not available