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Table 1 Substrates and applications of the corresponding alcohols

From: Gene mining-based identification of aldo–keto reductases for highly stereoselective reduction of bulky ketones

Entry Substrates Product configuration and application References
1a (R)-1b, a precursor of semi-synthetic penicillins, cephalosporins, vasodilators, fungicides, and sedatives Guo et al. (2010)
2a (R)-2b, a precursor of cyclandelate, hydrobenzole, or pemoline Kasprzak et al. (2016)
3a (R)-3b, a precursor of enalapril and lisinopril de Lacerda et al. (2006)
4a (S)-4b, a precursor of fluoxetine Engelking et al. (2006)
5a (S)-5b, a precursor of antitumor, anesthetic, antispasmodic, hepatotoxic, anti-inflammatory, and anti-HIV products Kizaki et al. (2008)