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Table 1 Substrates and applications of the corresponding alcohols

From: Gene mining-based identification of aldo–keto reductases for highly stereoselective reduction of bulky ketones

Entry

Substrates

Product configuration and application

References

1a

(R)-1b, a precursor of semi-synthetic penicillins, cephalosporins, vasodilators, fungicides, and sedatives

Guo et al. (2010)

2a

(R)-2b, a precursor of cyclandelate, hydrobenzole, or pemoline

Kasprzak et al. (2016)

3a

(R)-3b, a precursor of enalapril and lisinopril

de Lacerda et al. (2006)

4a

(S)-4b, a precursor of fluoxetine

Engelking et al. (2006)

5a

(S)-5b, a precursor of antitumor, anesthetic, antispasmodic, hepatotoxic, anti-inflammatory, and anti-HIV products

Kizaki et al. (2008)