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Fig. 5 | Bioresources and Bioprocessing

Fig. 5

From: Uridine modulates monoclonal antibody charge heterogeneity in Chinese hamster ovary cell fed-batch cultures

Fig. 5

Profiles of mAb lysine variant level and other basic variant level in different feed medium. a Lysine variant level; b other basic variant. (White bar) control condition; (shaded bar) uridine added condition. Other basic variant was detected with carboxypeptidase B treatment; lysine variant level was quantified by comparing the basic variant levels obtained from WCX with or without carboxypeptidase B treatment. The error bars indicate the standard deviations from three independent experiments and p-values were estimated by two-tailed Student’s t-test. *p < 0.05 relative to control; **p < 0.01 relative to control

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