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Table 1 Effect of uridine on cell growth and mAb production

From: Uridine modulates monoclonal antibody charge heterogeneity in Chinese hamster ovary cell fed-batch cultures

Cultures with different feed medium Peak VCD (×106 cells/mL) IVCC (109 cells day/L) Mab concentration (g/L) qmAb [mg/(109 cells day)]
Control 12.13 98.98 2.25 22.72
Uridine added 15.90** 148.64 ** 3.69 ** 24.81
  1. IVCC integral of viable cell concentration with time, qmAb specific mAb production
  2. p < 0.05 relative to control; ** p < 0.01 relative to control