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Table 3 Inhibition zone radius of M4018 and M4018 Δrim

From: Study on a two-component signal transduction system RimA1A2 that negatively regulates oxytetracycline biosynthesis in Streptomyces rimosus M4018

Antibiotics Inhibitory zone radius/mm
M4018 M4018 Δrim
OTC (mg/ml)
 20 10.33 ± 0.58 9.33 ± 0.58
 50 15.67 ± 1.15 13.67 ± 1.15
Kan (mg/ml)
 2.5 11.33± 0.58 8.67 ± 0.58
 10 16.67 ± 1.15 12.33 ± 1.15
 25 19.67 ± 1.53 15.00 ± 1.00
Cef (mg/ml)
 2.5
 10 6.00 ± 1.00 6.33 ± 0.58
 25 12.00 ± 0.00 11.67 ± 1.53
Ery (mg/ml)
 2.5 15.67 ± 1.15 16.00 ± 1.73
 10 18.00 ± 1.00 17.33 ± 1.15
 25 21.00 ± 1.00 20.33 ± 1.25
Amp (mg/ml)
 2.5
 10 8.67 ± 1.53 8.67 ± 0.58
 25 12.67 ± 0.58 12.33 ± 1.15
Chl (mg/ml)
 0.25 17.67 ± 0.58 14.33 ± 1.15
 0.5 21.00 ± 1.00 17.00 ± 0.00
 1 25.33 ± 0.58 20.00 ± 1.73
Rifa (mg/ml)
 2.5 17.67 ± 0.58 17.33 ± 1.53
 10 20.67 ± 1.15 19.00 ± 1.00
 25 21.67 ± 1.53 21.33 ± 1.53
  1. Numbers in italic represent significant increase in radius of inhibitory zone under the same experimental conditions. M4018: the parental strain, M4018 Δrim: the rimA1-disrupted mutant derived from M4018; the antibiotics used in the study include oxytetracycline (OTC), kanamycin (Kan), cefotaxime (Cef), erythromycin (Ery), ampicillin (Amp), chloramphenicol (Chl) and rifamycin (Rifa)