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Bioresources and Bioprocessing

Table 4 Reduction of OTC production under osmotic or oxidative stress condition

From: Study on a two-component signal transduction system RimA1A2 that negatively regulates oxytetracycline biosynthesis in Streptomyces rimosus M4018

 

M4018 (pIB-KA)

M4018 (pIB-KA-rim)

M4018 Δrim (pIB-KA)

M4018 Δrim (pIB-KA-rim)

KCl (%)

39

21

78

38

H2O2 (%)

54

76

33

64

  1. M4018 (pIB-KA): parental strain M4018 with a control plasmid pIB-KA; M4018 (pIB-KA-rim): rimA1A2-overexpressed mutant derived from M4018; M4018 Δrim (pIB-KA): rimA1-disrupted mutant M4018 Δrim with a control plasmid pIB-KA; M4018 Δrim (pIB-KA-rim): rimA1A2-complemented mutant derived from M4018 Δrim
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