Table 5 Studies related to chitosan blends and their application
From: Seafood waste: a source for preparation of commercially employable chitin/chitosan materials
S. no | Scaffold | Host and targeted defects | Outcomes | References |
|---|---|---|---|---|
1 | Chitosan + COG + PLGA | Skin defects in rats | Superior healing and greater expression of IHC, higher mechanical properties | Wang et al. (2013) |
2 | Chitosan membrane + COG | Human skin defects | Enhanced regeneration of skin wounds after 14 days | Sarkar et al. (2013) |
3 | Chitosan + silk fibroin | Sciatic nerve defects of adult Sprague–Dawley rats | Better nerve tissue regeneration | Gu et al. (2014) |
4 | Chitosan + gelatin | Skin injuries of rabbit | Adequate cytocompatibility in vitro, inflammation was exhibited in vivo | Han et al. (2014) |
5 | Chitosan + cellulose + silver nanoparticles | Skin injuries in the backs of Wistar rats | Efficient in the regeneration of skin wounds | Ahamed et al. (2015) |
6 | Chitosan + silk fibroin + HAP | Subcutaneous tissue of 6–8-week-old rat | Induced osteogenic differentiation | Shalumon et al. (2015) |
7 | Chitosan + gelatin | Subcutaneous tissue of mice | Enhanced bone-like tissue formation | Ji et al. (2015) |
8 | Chitosan sponges + copper | Calvarial defects in rats | Augmented bone neoformation | D’Mello et al. (2015) |
9 | Chitosan + alginate | subcutaneous tissue of mice | Boosted osteogenic differentiation | Caridade et al. (2015) |
10 | Chitosan + citric acid | tibial defects of rabbits | Prompted bone regeneration and adequate cytocompatibility | Ghosh et al. (2015) |
11 | COG + chitosan + PLGA + polyurethane | implantation in skin lesions on the backs of 2-month-old Sprague–Dawley rats | Improved regeneration of cutaneous tissue wounds and better mechanical performance | Wang et al. (2016) |
12 | Chitosan + COG + HAP | Implanted in calvarial defects of 6-week-old mice | Efficient bone regeneration and repairing of defects | Xie et al. (2016) |