Fig. 8

The structural analysis and electrostatic heat map (red = negatively charged, blue = positively charged, white = neutral) of the binding pocket of MfAgo for varied guides. The predicted binding pocket of MfAgo with a 5′-OH ssDNA guide (a), 5′-P ssDNA guide (b), and 5′-P ssRNA guide (c). d The binding pocket of TtAgo with a 5′-P ssDNA guide. e The binding pocket of MpAgo with a 5′-OH ssRNA guide