Fig. 1From: Cell-culture growth conditions resulting in the oxidation of a recombinant antigen-binding fragmenta DOE optimization study evaluating three process parameters; integrated viable cell density of CHO cells in 0.3 L bioreactors shown over 18 days of growth. b DOE optimization study evaluating three process parameters; cell viability of CHO cells in 0.3 L bioreactors shown over 18 days of growth. c DOE optimization study evaluating three process parameters; Viable cell density of CHO cells in 0.3 L bioreactors over 18 days of growth. d DOE optimization study evaluating three process parameters; Glucose concentrations during growth of CHO cells in 0.3 L bioreactors shown over 18 days of growth. e DOE optimization study evaluating three process parameters; Lactate concentrations during growth of CHO cells in 0.3 L bioreactors shown over 18 days of growth. f DOE optimization study evaluating three process parameters; Ammonium concentrations during growth of CHO cells in 0.3 L bioreactors shown over 18 days of growth. g DOE optimization study evaluating three process parameters; rFab titer in 0.3 L bioreactors shown over 18 days of growthBack to article page