Fig. 3From: Metabolic pathway analysis for in silico design of efficient autotrophic production of advanced biofuelsPhenotypic space of recombinant C. necator H16 synthesizing isobutanol (a) and hexadecanol (b) determined by elementary mode analysis. Each black circle represents individual pathway in which a linear combination of all pathways forms possible phenotypes existing in the recombinant strains with different product yields shown in colored surface plot. The x and y axes are uptake rate for H2 and CO2 of each pathway relative to its total gas uptake. c Reaction requirements of efficient pathways for synthesizing isobutanol and hexadecanol by the recombinant strains. Shown in green are core reactions necessary for product synthesis during growth and/or non-growth autotrophic conditions. These reactions are considered as potential target for overexpression. Reactions highlighted in brown are reactions not required for product synthesis, hence could potentially be target for deletionBack to article page