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Table 1 Initial experimental conditions

From: Bigdata analytics identifies metabolic inhibitors and promoters for productivity improvement and optimization of monoclonal antibody (mAb) production process

Condition

Reactor label

Expansion medium

Basal medium

Feed medium

1

V201, V202 and V203

Seed medium with 1X MSX

Basal medium

Feed medium

2

V204 and V205

Seed medium with 1X MSX

Basal medium

Feed medium with an increased concentration of Ser, Thr, Tyr, and Lys

3

V206, V207 and V208

Seed medium with 4X MSX

Basal medium

Feed medium

4

V209 and V210

Seed medium with 4X MSX

Basal medium

Feed medium with an increased concentration of Ser, Thr, Tyr, and Lys