Fig. 2

Expression of statin pump proteins improved MJ production. a MJ titer of strains expressing various statin pump proteins. b MJ productivity of strains expressing various statin pump proteins. Cells were cultured in YNM medium at an initial OD₆₀₀ of 1.0. Then 0.5% (w/v) methanol was fed every 24 h. Titers were measured in triplicate and experiments were performed three times. Statistical significance of MJ titer of each statin pump protein expression strain relative to J#9 was analyzed for each time point. *P < 0.05 at 24 h, ^#P < 0.05 at 48 h, ^×P < 0.05 at 72 h, ^⁜P < 0.05 at 96 h and n.s. not significant