Fig. 4From: Fungal statin pump protein improves monacolin J efflux and regulates its production in Komagataella phaffiiEvaluation of TapA function and MJ production of J#9-TapA and J#9 in bioreactor. a Time profiles of J#9-TapA and J#9 fermentation in a 5-L stirred tank bioreactor. Broth samples (2 mL) were collected at 8-h intervals and were analyzed twice to quantify cell growth and MJ concentration. Culture methods kept the same for both strains. Extracellular MJ level, intracellular MJ level and intracellular MJ percentage in strains of J#9 (b) and J#9-TapA (c). The bioreactor fermentation experiments were conducted two timesBack to article page