Table 2 Proposed classification of Bacillaceae bacteriocins in class II (post-translationally unmodified peptides)

Type A (cystibiotic)

Pediocin-like bacteriocins contains medium-length bacteriocins (37–48 residues) with strong antilisterial activity. The group contain a conserved N-terminal sequence—the YGNGV “pediocin box”—and one or two intra-chain disulfide bonds

Coagulin (B. coagulans)

Entomocin 110 (B. thuringiensis subsp. entomocidus)

SRCAM 37 (P. polymyxa NRRL B-30507)

SRCAM 602 (P. polymyxa NRRL B-30509)

SRCAM 1580 (B. circulans NRRL B-30644

Thermocins (Geobacillus stearothermophilus)

Cherif et al. (2008), Pokusaeva et al. (2009), Hyronimus et al. (1998), Svetoch et al. (2005)

Type B (thuricin-like peptide)

Bacteriocins shared similar N-terminal sequence with the anti-Listeria bacteriocin thuricin S)

Thuricin S (B. thuringiensis HD198)

Thuricin17 (B. thuringiensis)

Bacthuricin F4 (B. thuringiensis)

Cerein MRX1 (B. cereus)

Thuricin 7 (B. thuringiensis BMG1.7)

EntomocinHD9 (B. thuringiensis subsp. entomocidus)

Tochicin (B. thuringiensis subsp. tochigiensis HD868)

Thuricin HD2 (B. thuringiensis subsp. thuringiensis)

Cherif et al. (2008), Salazar-Marroquín et al. (2016)

Type C

Two-peptide bacteriocins whose antimicrobial activity relies on the complementary action of the two different peptides

Thuricin 439 (B. thuringiensis B439)

Huang et al. (2016)

Type D

One-peptide noncyclic bacteriocins that show no sequence similarity to other bacteriocins. It also includes a leaderless bacteriocin subgroup whose members are different from most bacteriocins in that they do not involve an N-terminal leader sequence for exporting nonpediocin linear one-peptide

Cerein 7A (B. cereus)

Cerein 7B (B. cereus)

Lichenin (B. licheniformis)

BLIS (Virgibacillus salexigens)

Pattnaik et al. (2001), Ovchinnikov et al. (2016), Luca et al. (2002)