Table 3 Proposed classification of Bacillaceae bacteriocins in class III, IV and V
From: Biomanufacturing process for the production of bacteriocins from Bacillaceae family
Class | Description | Bacteriocin (strain) | References |
|---|---|---|---|
Class III | Large protein, molecular weights of more than 30Â kDa and sensitive to heat | Megacin A-216 (B. megaterium 216) Megacin A-1921 (B. megaterium 1921) SW1-1 (Bacillus sp. SW1-1) | |
Class IV | Complex bacteriocins composed of lipid/carbohydrates moiety. Mostly synthesized by LAB | Bacteriocin H4 (Bacillus sp.) | Compaoré et al. (2013) |
Class V | Peptides consisting of ribosomally synthesized nonmodified head-to-tail-ligated cyclic peptides of their backbone. This process of leader peptide removal, circularization, and secretion putatively involves dedicated enzymatic reactions Cyclization by formation of a peptide bond between the N and C termini of a processed prepeptide Most circular bacteriocins probably adopt a common 3D structure consisting of several α-helices encompassing a hydrophobic core | Amylocyclicin (B. amyloliquefaciens FZB42) | Liu et al. (2013), Scholz et al. (2014), Gabrielsen et al. (2014), Martin-Visscher et al. (2011) |