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Table 2 Bikaverin production (mg/L) by F. oxyporum CCT7620 for each experimental condition defined by the central composite rotational design

From: Modeling bikaverin production by Fusarium oxysporum CCT7620 in shake flask cultures

Run

Temperature (°C)

Agitation (rpm)

Rice flour (g/L)

Bikaverin production (mg/L)

Coded

Real

Coded

Real

Coded

Real

0 h

24 h

48 h

72 h

96 h

1

− 1

24

− 1

115

− 1

30

0

0

0

44.53

75.45

2

+ 1

32

− 1

115

− 1

30

0

0

0

100.34

132.74

3

− 1

24

+ 1

245

− 1

30

0

0

0

127.90

260.15

4

+ 1

32

+ 1

245

− 1

30

0

0

0

0

140.43

5

− 1

21

− 1

115

+ 1

70

0

0

0

37.86

0

6

+ 1

32

− 1

115

+ 1

70

0

0

0

38.11

0

7

− 1

24

+ 1

245

+ 1

70

0

0

0

53.24

111.02

8

+ 1

32

+ 1

245

+ 1

70

0

0

0

0

103.14

9

− 1.68

21

0

180

0

50

0

0

0

42.33

138.36

10

+ 1.68

35

0

180

0

50

0

0

0

32.77

0

11

0

28

− 1.68

71

0

50

0

0

0

0

0

12

0

28

+ 1.68

289

0

50

0

0

0

269.89

293.36

13

0

28

0

180

− 1.68

16.3

0

0

94.53

247.20

269.90

14

0

28

0

180

+ 1.68

83.6

0

0

0

0

46.32

15

0

28

0

180

0

50

0

0

32.29

103.67

139.12

16

0

28

0

180

0

50

0

0

61.61

133.03

158.13

17

0

28

0

180

0

50

0

0

56.92

121.98

171.23