Table 2 Ranges of agitation speeds for BHK-21 cells cultured in the different 5-L bioreactors as required by the optimal key hydrodynamic parameters

5L-EE-0.45

\(8.5{0} \le \gamma_{{{\text{imp}}}} \le 11.0\)(s⁻¹)

_{73.2 ≤ N ≤ 94.7}

_{88.4 ≤ N ≤ 94.7}

\(\varepsilon_{\tan } \ge 0.0013\)(m² s⁻³)

_{N ≥ 88.4}

5L-EE-0.5

\(8.5{0} \le \gamma_{{{\text{imp}}}} \le 11.0\)(s⁻¹)

_{64.0 ≤ N ≤ 82.8}

_{75.4 ≤ N ≤ 82.8}

\(\varepsilon_{\tan } \ge 0.0013\)(m² s⁻³)

_{N ≥ 75.4}

5L-PBT-0.5

\(8.5{0} \le \gamma_{{{\text{imp}}}} \le 11.0\)(s⁻¹)

_{89.4 ≤ N ≤ 115.7}

_{96.3 ≤ N ≤ 115.7}

\(\varepsilon_{\tan } \ge 0.0013\)(m² s⁻³)

_{N ≥ 96.3}