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Bioresources and Bioprocessing
Fig. 3 | Bioresources and Bioprocessing

Fig. 3

From: Targeted accumulation of selective anticancer depsipeptides by reconstructing the precursor supply in the neoantimycin biosynthetic pathway

Fig. 3

HPLC–MS analysis of UAT-B production in the fermentation extracts of the ΔnatO strain fed 3-HBA or containing different nat-hyg3 gene expression cassettes: A4p_nat-hyg5, kasOp*_nat-hyg5 or ermEp*_nat-hyg5. The HPLC–MS data are displayed with the mass extraction of [M+Na]+ m/z 676.4 for UAT-B. The exact UAT-B production titres displayed were obtained by using UPLC-QqQ/MS analysis. All the production titre values shown are the mean ± standard deviation of triplicate determinations

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