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Bioresources and Bioprocessing
Fig. 3 | Bioresources and Bioprocessing

Fig. 3

From: In vivo toxicity and antitumor activity of newly green synthesized reduced graphene oxide/silver nanocomposites

Fig. 3

Effect of rGO/Ag nanocomposite biosynthesized by E. coli on mice liver. A silver content in the hepatic tissue. B TEM of control hepatocytes showing nuclei (N) and mitochondria (M). C TEM of hepatocytes from mice treated with rGO/AgNC showing cytoplasmic vacuolation (V) associated with the presence of silver nanoparticles (NP). Liver function was assessed by assessing serum ALT (D), AST (E) and albumin (Fig. 6D). Histopathologic effect in livers of mice treated with rGO/AgNC (G), compared to the control livers (F). Abbreviations: PV, portal vein; CV, central vein; straight arrows show mild inflammatory leucocyte infiltration; curved arrows show areas of pycnotic nuclei and focal necrosis. * denotes statistically significant different value from the control one (t-test)

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