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Bioresources and Bioprocessing
Fig. 4 | Bioresources and Bioprocessing

Fig. 4

From: In vivo toxicity and antitumor activity of newly green synthesized reduced graphene oxide/silver nanocomposites

Fig. 4

Reduced GO/Ag nanocomposites biosynthesized by E. coli are largely taken up by the kidney. TEM of convoluted tubules epithelia A, control; B and C, nanocomposite-treated) showing shrinking nuclei (N), mitochondrial aberration (M) and thickened basement membranes (arrows) in B and C, compared to that in A. D silver content in the renal tissue. E Nanocomposite treatment increases serum creatinine. The * in D and E denotes statistically significant different value from the control one (unpaired t-test). Histopathologic effect in kidneys of mice treated with rGO/AgNC (G), compared to the control (F), show dilated Bowman space of the renal corpuscles (RC) and degenerated and necrotic tubular epithelia (arrows)

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