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Bioresources and Bioprocessing
Fig. 4 | Bioresources and Bioprocessing

Fig. 4

From: Identification of a novel metabolic engineering target for carotenoid production in Saccharomyces cerevisiae via ethanol-induced adaptive laboratory evolution

Fig. 4

Differentially expressed genes generated by transcriptome analysis in YPM media after 24 h of incubation. a Volcano plot of the differentially expressed genes in M3. The horizontal coordinate represented the fold change, and the vertical coordinate represented a significant difference Padjust (logarithmic transformation at the base of 10). Red dots represented up-regulated genes, and green dots represented down-regulated genes. b, c Histogram of GO enrichment and KEGG pathway enrichment analysis. The vertical coordinate shows the enriched GO terms and the pathway names, and the horizontal coordinate represents the number of genes and Padjust of differentially expressed genes in the term and the pathway, respectively. d Overview of significantly changed genes in metabolic pathways. Pentose phosphate pathway (oxidative phase, yellow; non-oxidative phase, blue): GND, glucose 6-phosphate dehydrogenase; 6PGL, 6-phosphogluconolactonase; 6PGD, 6-phosphogluconate dehydrogenase; TKL, transketolase; TAL, transaldolase. Glycolysis and gluconeogenesis (green): HXK, hexokinase; PGI, phosphoglucose isomerase; INO1, inositol-3-phosphate synthase; PFK, phosphofructokinase; FBP1, fructose 1,6-bisphosphatase; FBPA, fructose-bisphosphate aldolase; GAPD: glyceraldehyde phosphate dehydrogenase; PGK, phosphoglycerate kinase; PGM, phosphoglycerate mutase; ENO, enolase

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