Fig. 6

Structure of bornyl diphosphate synthase. a Stereoplot of unliganded (+)-bornyl diphosphate synthase (PDB ID: 1N1B), looking into the active site in the α domain (blue). Disordered polypeptide segments are indicated by dashed lines and the β domain is in green. b Active site of unliganded (+)-bornyl diphosphate synthase. c Active site of the (+)-bornyl diphosphate synthase complexed with inorganic pyrophosphate and Mg²⁺ (green ball) (PDB ID: 1N1Z). These conformational differences between unliganded enzyme and liganded enzyme mainly include the N-terminal segment (cyan) and some loops (red) which help ‘close’ the active site