Fig. 2From: Biotechnological applications of S-adenosyl-methionine-dependent methyltransferases for natural products biosynthesis and diversificationReactions of recently discovered novel methyltransferases. These enzymes are mainly discovered through genomic and chemical screening (Table 1). a Methylation of nocamycin E by NcmP to produce nocamycin I. The structure of Nocamycin II is shown. b Novel radical-SAM mediated cyclopropanase system to produce the antibiotic CC1065. c Network of methyltransferases involved in xantholipin biosynthesis. d Network of methyltransferases involved in gentamicin C biosynthesis. The starting compound is 3-dehydro-3-oxo-gentamicin A2 (DAA2)Back to article page