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Bioresources and Bioprocessing

Table 2 Comparison of CHMOAcineto-Mut production in E. coli and P. pastoris

From: Secretory expression of cyclohexanone monooxygenase by methylotrophic yeast for efficient omeprazole sulfide bio-oxidation

Strain

Fermentation time (h)

Peak activity (U/L)

Productivity (U L−1 h−1)

CHMO constitution (%)

Cell disruption

Costa (CNY/kU)

P. pastoris X33

119 (103)b

1728  ±  63

14.5

85

N

0.66

E. coli BL21 (DE3)

15.5 (10.5)b

855  ±  133

55.1

50

Y

2.32

  1. aFor calculation details of the cost for fermentation and preparation of CHMOAcineto-Mut from different host, see Additional file 1: Table S2
  2. bInduction time
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