Concurrent production of glycyrrhetic acid 3-O-mono-β-d-glucuronide and lignocellulolytic enzymes by solid-state fermentation of a plant endophytic Chaetomium globosum

Bioresources and Bioprocessing

Table 1 Analysis of lignocellulose-degrading enzymatic activities and production of GAMG under optimal fermentation conditions

	Enzymes	Max enzymatic activity (U/g)	Days (d)	P^a (U/g/d)	P^b (mg/g/d)
Non-optimization	CMCase	29.17 ± 1.01	10	2.93 ± 0.68	0.9 ± 0.03
	FPase	234.63 ± 4.28	7	33.52 ± 0.58
	β-Glucosidase	6.81 ± 0.30	22	0.31 ± 0.02
	Xylanase	72.52 ± 4.00	7	10.36 ± 0.44
	GUSase	264.17 ± 12.17	20	13.21 ± 0.69
Optimization	CMCase	33.67 ± 2.48	5	6.74 ± 0.88*
	FPase	245.80 ± 13.40	3	81.93 ± 2.36*
	β-Glucosidase	5.78 ± 0.69	20	0.29 ± 0.03	2.1 ± 0.07*
	Xylanase	83.44 ± 3.76	3	27.81 ± 1.78*
	GUSase	271.42 ± 6.54	10	27.15 ± 2.06*

^aThe production of lignocellulolytic enzymes when reaching maxim enzymatic activity
^bThe production of GAMG when the percent conversion of glycyrrhizin reaches 90%.
*P values analyzed by t test are statistically significant for a confidence level of 95% (P < 0.05)