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Table 2 HLADH–SBFC-catalyzed oxidative lactonization reactions

From: Biosynthesis of lactones from diols mediated by an artificial flavin

  1. Reaction conditions: diols (20 mM), NAD+ (0.1 mM), SBFC (0.05 mM), HLADH (0.3 g L−1), and catalase (20 U/mL) in 1 mL of aqueous Tris–HCl buffer (50mM, pH 8.0) at 30 °C
  2. aYield were determined by GC and HPLC
  3. bThe ee values of lactones were determined by chiral HPLC and GC