Skip to main content
Fig. 1 | Bioresources and Bioprocessing

Fig. 1

From: Structure-guided protein engineering of ammonia lyase for efficient synthesis of sterically bulky unnatural amino acids

Fig. 1

EcMAL residues chosen for saturation mutagenesis marked in the homology model built by the crystal structure of MAL (PDB: 1KKR). A Active site mutation sites (yellow) selected on the basis of induced fit docking of amine 1 (green). B Residues surrounding the substrate access tunnel likewise chosen for mutagenesis (blue). The above residues were obtained through the molecular docking of Yasara and the channel recognition function of CAVER 3.0, respectively

Back to article page