Fig. 1From: Development of a plasmid stabilization system in Vibrio natriegens for the high production of 1,3-propanediol and 3-hydroxypropionateMetabolic engineering strategies for developing V. natriegens to produce 1,3-PDO. The deleted genes are shown with cross marks. A heterologous 1,3-PDO synthesis pathway is introduced by overexpressing genes encoding glycerol dehydratase (dhaBCE) and its activator (gdrAB) and a NADPH-dependent alcohol dehydrogenase (yqhD). A plasmid stabilization system is developed by deleting the chromosomal glpD gene encoding glycerol-3-phosphate dehydrogenase and expressing the corresponding gene in the expression vectorBack to article page