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Table 1 The number of differential proteins between 2D monolayer culture and 3D MTS before and after the 5-FU treatment

From: Multi-omics analysis defines 5-fluorouracil drug resistance in 3D HeLa carcinoma cell model

Control group Experimental group Up Down Sum
2D monolayer 3D MTS 206 161 367
2D monolayer + 5-FU 3D MTS + 5-FU 185 103 288
2D monolayer 2D monolayer + 5-FU 51 82 133
3D MTS 3D MTS + 5-FU 8 19 27