Table 2 The number of differential metabolites between 2D monolayer culture and 3D MTS before and after the 5-FU treatment
From: Multi-omics analysis defines 5-fluorouracil drug resistance in 3D HeLa carcinoma cell model
Control group | Experimental group | Up | Down | Sum |
|---|---|---|---|---|
2D monolayer | 3D MTS | 44 | 55 | 99 |
2D monolayer + 5-FU | 3D MTS + 5-FU | 56 | 35 | 91 |
2D monolayer | 2D monolayer + 5-FU | 27 | 80 | 107 |
3D MTS | 3D MTS + 5-FU | 41 | 35 | 76 |