Table 3 Intra-day and inter-day accuracy and precision of COS 2 and COS 3 in serum
From: Pharmacokinetics, bioavailability and tissue distribution of chitobiose and chitotriose in rats
Analyte | Nominal concentration (μg /mL) | Intra-day (n = 5) | Inter-day (n = 5) | Inter-day (n = 5) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Calculated concentration (µg /mL) | Accuracy (RE%) | Precision (RSD%) | Calculated concentration (µg /mL) | Accuracy (RE%) | Precision (RSD%) | Nominal concentration (µg /mL) | Calculated concentration (µg /mL) | Accuracy (RE%) | Precision (RSD%) | ||
COS 2 | 2. | 2. ± 0.073 | 1.39 | .55 | 1.81 ± 0.04 | − 9.41 | 1.94 | 2.00009503 | 1. ± 0.12 | − 2.36 | 6.Accuracy (RE%)05 |
0.20 | 0.20 ± 0.01 | − 1.87 | 0.04 | 0.20 ± 0.01 | 0.16 | 5.62 | 0.20 | 0.20 ± 0.01 | 0.23 | 4.03 | |
0.02 | 0.02 ± 0.00 | 2.59 | 0.08 | 0.02 ± 0.00 | 7.38 | 7.09 | 0.02 | 0.02 ± 0.00 | − 2.12 | 4.08 | |
COS 3 | 5.00 | 5.19 ± 0.36 | 3.84 | 0.07 | 5.08 ± 0.59 | 1.60 | 11.63 | 5.00 | 4.88 ± 0.20 | − 2.38 | 4.00 |
0.50 | 0.55 ± 0.03 | 9.10 | 0.05 | 0.53 ± 0.01 | 6.52 | 2.60 | 0.50 | 0.49 ± 0.05 | − 2.03 | 9.20 | |
0.05 | 0.06 ± 0.00 | 11.06 | 0.07 | 0.05 ± 0.00 | 8.63 | 7.38 | 0.05 | 0.05 ± 0.00 | 5.35 | 3.43 | |