Table 4 Stability results of COS 2 and COS 3 under two different storage conditions
From: Pharmacokinetics, bioavailability and tissue distribution of chitobiose and chitotriose in rats
Stability test | Analyte | Nominal concentration (μg/mL) | Calculated concentration (μg/mL) | Accuracy (RE%) | Precision (RSD%) |
|---|---|---|---|---|---|
Three freeze–thaw cycles | COS 2 | 2.00 | 1.88 ± 0.15 | − 5.81 | 7.89 |
0.20 | 0.19 ± 0.01 | − 3.49 | 3.71 | ||
0.02 | 0.02 ± 0.00 | − 1.97 | 7.41 | ||
COS 3 | 5.00 | 4.87 ± 0.35 | − 2.69 | 7.23 | |
0.50 | 0.49 ± 0.05 | − 2.40 | 9.28 | ||
0.05 | 0.06 ± 0.00 | 14.16 | 6.61 | ||
Autosampler for 24 h | COS 2 | 2.00 | 1.86 ± 0.05 | − 6.93 | 2.50 |
0.20 | 0.20 ± 0.00 | 1.11 | 2.20 | ||
0.02 | 0.02 ± 0.00 | 6.80 | 7.09 | ||
COS 3 | 5.00 | 5.20 ± 0.56 | 4.03 | 10.76 | |
0.50 | 0.51 ± 0.04 | 1.15 | 8.36 | ||
0.05 | 0.06 ± 0.00 | 14.30 | 3.81 |